융합의과학과
의생명과학 전공 참여교수 및 프로필입니다.
■학력 및 경력
2006 의학박사 (해부학), 제주대학교
2006-2010 박사 후 연구원, 가천대학교, 이길여암당뇨연구원
2011-현재 부교수, 교수 가천대학교
■소개
기능단백체 네트워크연구실에서는 피부, 혈관, 지방, 염증 및 신경질환 치료를 위한 포괄적 개념의 중개 연구를 수행하고 있다. 특히 환자맞춤형 치료를 위한 의료기기와 건강기능성식품 개발을 위하여 나노과학, 기능단백체학 등의 기술을 이용하여 다양한 수준에서의 기전연구를 포함한 중개연구를 수행하고 있다. 뿐만 아니라 개발된 연구 결과는 식품의약품안전처의 인허가를 획득하여 임상연구를 수행 후 산업화에 활동되고 있다.
■키워드
재생의학, 의료기기, 건강기능성식품, 기능단백체, 분자이미징, 시스템생물학
■최근 연구업적(2022)
1. A Mixture of Topical Forms of Polydeoxyribonucleotide, Vitamin C, and Niacinamide Attenuated Skin Pigmentation and Increased Skin Elasticity by Modulating Nuclear Factor Erythroid 2-like 2 (2022) Molecules. 14;27(4):1276
2. Radiofrequency Irradiation Mitigated UV-B-Induced Skin Pigmentation by Increasing Lymphangiogenesis (2022) Molecules, 11;27(2):454
3. Ecklonia cava extracts decrease hypertension-related vascular calcification by modulating PGC-1α and SOD2 (2022) Biomed Pharmacother. 153:113283
4. Anti-Obesity Effects of Multi-Strain Probiotics in Mice with High-Carbohydrate Diet-Induced Obesity and the Underlying Molecular Mechanisms Nutrients. (2022) 5;14(23):5173
5. Ishophloroglucin A, Isolated from Ishige okamurae, Alleviates Dexamethasone-Induced Muscle Atrophy through Muscle Protein Metabolism In Vivo (2022) Mar Drugs. 22;20(5):280
6. Reversibility of sarcopenia by Ishige okamurae and its active derivative diphloroethohydroxycarmalol in female aging mice Biomed Pharmacother. (2022) 152:113210
7. The Combination of Niacinamide, Vitamin C, and PDRN Mitigates Melanogenesis by Modulating Nicotinamide Nucleotide Transhydrogenase (2022) Molecules. 2;27(15):4923
8. Pyrogallol-Phloroglucinol-6, 6-Bieckol Restored Primary Cilia Length, Which Was Decreased by High-Fat Diet in Visceral Adipose Tissue and Decreased Adipogenesis (2022) Int J Endocrinol. 16;2022:8486965
9. High-Intensity Focused Ultrasound Induces Adipogenesis via Control of Cilia in Adipose-Derived Stem Cells in Subcutaneous Adipose Tissue (2022) Int J Mol Sci. 9;23(16):8866
10. Diphlorethohydroxycarmalol Derived from Ishige okamurae Improves Behavioral and Physiological Responses of Muscle Atrophy Induced by Dexamethasone in an In-Vivo (2022) Model Pharmaceutics. 27;14(4):719
11. Effect of Intake of Leucine-Rich Protein Supplement in Parallel with Resistance Exercise on the Body Composition and Function of Healthy Adults (2022) Nutrients. 26;14(21):4501
12. Combined Treatment of Monopolar and Bipolar Radiofrequency Increases Skin Elasticity by Decreasing the Accumulation of Advanced Glycated End Products in Aged Animal Skin (2022) Int J Mol Sci. 10;23(6):2993
13. Stem Cell and Exosome Therapy in Pulmonary Hypertension (2022) Korean Circ J. 52(2):110-122